Description

2-Amino-3-Chloro-Propionohydroxamic-15N,D3 Acid is a stable isotope-labeled derivative of a hydroxamic acid, specifically incorporating 15N and deuterium (D3) atoms. This compound is of critical importance for use as an internal standard in quantitative mass spectrometry, enabling highly accurate and sensitive analytical measurements. It is primarily needed by research scientists and quality control laboratories in the pharmaceutical, agrochemical, and advanced material sectors for method development, pharmacokinetic studies, and metabolic pathway analysis.

Application

• Internal Standard for LC-MS/MS: Essential for precise quantification of the unlabeled parent compound in complex biological matrices like plasma, urine, and tissue homogenates.
• Metabolite Identification & Tracing: Used in drug metabolism and pharmacokinetics (DMPK) studies to track and identify metabolites using isotope pattern recognition.
• Proteomics & Biomarker Research: Serves as a labeled reagent or standard in the study of enzyme activity and protein interactions where hydroxamic acid motifs are involved.
• Method Development & Validation: Provides a critical reference point for developing robust, regulatory-compliant analytical methods in pharmaceutical R&D and quality control.
• Chemical Synthesis Research: Acts as a building block or labeled precursor for the synthesis of novel isotopically labeled compounds for research purposes.

Basic Information

Product Name	2-Amino-3-Chloro-Propionohydroxamic-15N,D3 Acid
CAS No.	1794713-69-1
Molecular Formula	C₃H₂D₃¹⁵NClNO₂
Molecular Weight	Contact for details
Synonyms	2-Amino-3-chloro-N-hydroxypropanimidic-15N,D3 acid; 3-Chloro-2-aminopropanehydroxamic-15N,D3 acid; 2-Amino-3-chloropropanehydroxamic-15N,D3 acid; 15N,D3-2-Amino-3-chloropropionohydroxamic acid; Isotopically labeled hydroxamic acid; [15N,D3]-ACPA; Stable Isotope Labeled Internal Standard CAS 1794713-69-1
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-Chloro-Propionohydroxamic-15N,D3 Acid is produced and analyzed under strict quality management protocols to ensure the highest isotopic and chemical purity for analytical applications. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to confirm isotopic enrichment and chemical identity. Certificates of Analysis (COA) detailing lot-specific purity, isotopic abundance, and analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This hygroscopic and potentially light-sensitive material should be kept in a cool, dry place under an inert atmosphere upon opening to maintain stability and isotopic integrity. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (15N)	≥ 98 atom %
Isotopic Purity (D)	≥ 98 atom % D
Chemical Purity (Assay)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.