Description

Benzoic Acid, 3-Fluoro-2-Hydroxy-4-Methoxy- is a strategically substituted benzoic acid derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its unique trifunctional molecular architecture, combining a carboxylic acid, a phenolic hydroxyl, and a fluorine atom on a methoxy-substituted aromatic ring, enabling precise chemical modifications. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty dyes and liquid crystal materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure or side-chain component in the synthesis of specialty chemicals for electronic displays and optoelectronic devices.
• Dye & Pigment Manufacturing: Acts as a precursor for synthesizing complex, high-performance organic dyes and pigments with tailored color and fastness properties.
• Polymer Modification: Employed to introduce functional groups into polymer chains, enhancing properties like adhesion, solubility, or biocompatibility for specialty resins and coatings.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science research for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	Benzoic Acid, 3-Fluoro-2-Hydroxy-4-Methoxy-
CAS No.	1784962-35-1
Molecular Formula	C8H7FO4
Molecular Weight	186.14 g/mol
Synonyms	3-Fluoro-2-hydroxy-4-methoxybenzoic acid; 2-Hydroxy-3-fluoro-4-methoxybenzoic acid; 4-Methoxy-3-fluoro-2-hydroxybenzoic acid; 3-Fluoro-4-methoxysalicylic acid; 3-Fluoro-2-hydroxy-p-anisic acid; 3-Fluoro-4-methoxy-2-hydroxybenzoic acid; Benzoic acid, 2-hydroxy-3-fluoro-4-methoxy-
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 3-Fluoro-2-Hydroxy-4-Methoxy- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance for sensitive synthesis applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request, supporting compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.