Description

3-Chloro-2-Fluoro-6-Methoxy-Benzoic Acid is a high-purity, multi-functional benzoic acid derivative distinguished by its unique halogen and methoxy substitution pattern. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates with halogenated aromatic cores.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers where specific substitution patterns are required.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis projects and scale-up production under cGMP or ISO standards.
• Academic and R&D Laboratories: Used in medicinal chemistry and organic synthesis research for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	3-Chloro-2-Fluoro-6-Methoxy-Benzoic Acid
CAS No.	1782016-34-5
Molecular Formula	C8H6ClFO3
Molecular Weight	204.58 g/mol
Synonyms	2-Fluoro-3-chloro-6-methoxybenzoic acid; 6-Methoxy-3-chloro-2-fluorobenzoic acid; Benzoic acid, 3-chloro-2-fluoro-6-methoxy-; 3-Chloro-2-fluoro-6-methoxybenzoic acid; 2-Fluoro-3-chloro-6-methoxy-benzoic acid; 3-Chloro-2-fluoro-6-methoxybenzoic acid (CAS 1782016-34-5)
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoro-6-Methoxy-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for demanding R&D and scale-up applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We can supply material compliant with various project requirements, including those for cGMP intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.