Description

Benzoic Acid, 4-(Difluoromethyl)-3-Fluoro- is a high-value, multi-fluorinated aromatic building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers seeking to introduce specific fluorine motifs to modulate the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily utilized in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where precise fluorination is required.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and pesticides with enhanced activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a fluorinated core structure for electronic and display materials requiring specific dielectric and optical properties.
• Polymer Modification: Employed to introduce fluorine groups into polymer chains, improving chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: An essential reagent in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Fluorinated Dye & Pigment Precursor: Used in the synthesis of specialty colorants with improved lightfastness and solubility.

Basic Information

Product Name	Benzoic Acid, 4-(Difluoromethyl)-3-Fluoro-
CAS No.	1780188-78-4
Molecular Formula	C8H5F3O2
Molecular Weight	190.12 g/mol
Synonyms	3-Fluoro-4-(difluoromethyl)benzoic acid; 4-(Difluoromethyl)-3-fluorobenzoic acid; 2-Fluoro-α,α-difluoro-p-toluic acid; Benzoic acid, 3-fluoro-4-(difluoromethyl)-; 1780188-78-4; FC-1043 (Potential R&D code); DFMFBA (Abbreviation)
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-(Difluoromethyl)-3-Fluoro- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF for moisture content, to ensure it meets the exacting standards required for R&D and scale-up. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.