Description

2-Fluoro-5-Methyl-3-(Trifluoromethyl)Benzoic Acid is a high-value fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart desirable properties such as enhanced metabolic stability and lipophilicity to final compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of modern herbicides, fungicides, and insecticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to modify dielectric anisotropy and viscosity.
• Organic Electronic Materials: Employed in the development of organic semiconductors, OLED materials, and photovoltaic cells, where fluorination tunes electronic properties and stability.
• Advanced Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, including polyamides and polyesters, to enhance chemical resistance and thermal stability.
• Chemical Research & Development: A versatile reagent for constructing complex molecular architectures in academic and industrial R&D settings, enabling structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Fluoro-5-Methyl-3-(Trifluoromethyl)Benzoic Acid
CAS No.	1706435-08-6
Molecular Formula	C9H6F4O2
Molecular Weight	222.14 g/mol
Synonyms	2-Fluoro-5-methyl-3-(trifluoromethyl)benzoic acid; 3-Trifluoromethyl-2-fluoro-5-methylbenzoic acid; 2-Fluoro-α,α,α-trifluoro-5-methyl-m-toluic acid; 1706435-08-6; Benzoic acid, 2-fluoro-5-methyl-3-(trifluoromethyl)-; 5-Methyl-2-fluoro-3-trifluoromethylbenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Methyl-3-(Trifluoromethyl)Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA), including purity by HPLC, identity confirmation (IR, NMR), and impurity profile, is supplied with each shipment to guarantee reproducible performance and supply chain traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.