Description

(4-(n-Cyclopropylsulfamoyl)-3-Fluorophenyl)Boronic Acid is a high-purity, advanced pharmaceutical intermediate and building block featuring a unique sulfamoyl-fluorophenyl boronic acid scaffold. This compound matters for its critical role in modern medicinal chemistry, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex, drug-like molecules. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for drug discovery programs.
• Suzuki-Miyaura Cross-Coupling Reagent: Used to form carbon-carbon bonds, essential for constructing biaryl structures common in many drug candidates.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a precursor for creating advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Process Chemistry & Scale-up: Supports the development of robust, scalable synthetic routes from laboratory to pilot plant scale.

Basic Information

Item	Detail
Product Name	(4-(n-Cyclopropylsulfamoyl)-3-Fluorophenyl)Boronic Acid
CAS No.	1704096-55-8
Molecular Formula	C9H11BFNO4S
Molecular Weight	259.06 g/mol
Synonyms	4-(N-Cyclopropylsulfamoyl)-3-fluorobenzeneboronic acid; 3-Fluoro-4-(N-cyclopropylsulfamoyl)phenylboronic acid; [4-(Cyclopropylsulfamoyl)-3-fluorophenyl]boronic acid; B-[4-(Cyclopropylsulfamoyl)-3-fluorophenyl]boronic acid; (4-Cyclopropylsulfamoyl-3-fluorophenyl)boronic Acid; CP-Sulfamoyl-F-PhB(OH)2; 1704096-55-8
EINECS	Contact for details

Quality Control

Our (4-(n-Cyclopropylsulfamoyl)-3-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.