Description

(4-(N,n-Dimethylsulfamoyl)-3-Fluorophenyl)Boronic Acid is a high-purity, functionalized boronic acid derivative designed for advanced synthetic chemistry. This compound is a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds via the versatile Suzuki-Miyaura cross-coupling reaction. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for drug discovery and development programs.
• Suzuki-Miyaura Cross-Coupling: Serves as an essential organoboron reagent for constructing biaryl and heterobiaryl structures in medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific fluorinated and sulfonamide motifs.
• Material Science: Potential monomer or building block for creating advanced polymers and organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale commercial batches.

Basic Information

Product Name	(4-(N,n-Dimethylsulfamoyl)-3-Fluorophenyl)Boronic Acid
CAS No.	1704096-37-6
Molecular Formula	C8H12BFNO4S
Molecular Weight	247.06 g/mol
Synonyms	[4-(Dimethylsulfamoyl)-3-fluorophenyl]boronic acid; 3-Fluoro-4-(N,N-dimethylsulfamoyl)phenylboronic acid; (4-Dimethylsulfamoyl-3-fluorophenyl)boronic acid; B-[4-(Dimethylsulfamoyl)-3-fluorophenyl]boronic acid; 4-(Dimethylsulfamoyl)-3-fluorobenzeneboronic acid; N,N-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluorobenzenesulfonamide (Pinacol ester precursor)
EINECS	Contact for details

Quality Control

Our (4-(N,n-Dimethylsulfamoyl)-3-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.