Description

(3-Fluoro-4-(n-Isopropylsulfamoyl)Phenyl)Boronic Acid is a high-value, multi-functional organoboron building block designed for advanced synthetic chemistry. Its core value lies in the strategic combination of a boronic acid group for Suzuki-Miyaura cross-coupling and a fluoro-substituted sulfonamide moiety, enabling precise molecular construction and functionalization. This compound is essential for researchers and process chemists in pharmaceutical R&D and agrochemical discovery who require sophisticated intermediates for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting kinase inhibition, enzyme modulation, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its unique fluorine and sulfonamide pharmacophores.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials via its reactive boronic acid handle.
• Chemical Biology & Probe Development: Employed in the construction of molecular probes and bioconjugates for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form biaryl and heterobiaryl structures central to modern medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for client projects.

Basic Information

Product Name	(3-Fluoro-4-(n-Isopropylsulfamoyl)Phenyl)Boronic Acid
CAS No.	1704096-35-4
Molecular Formula	C9H13BFNO4S
Molecular Weight	269.08 g/mol
Synonyms	[4-(Isopropylsulfamoyl)-3-fluorophenyl]boronic acid; 3-Fluoro-4-(N-isopropylsulfamoyl)benzeneboronic acid; B-[3-Fluoro-4-[(1-methylethyl)sulfamoyl]phenyl]boronic acid; (3-Fluoro-4-(isopropylsulfamoyl)phenyl)boronic acid; Boronic acid, B-[3-fluoro-4-[(1-methylethyl)sulfamoyl]phenyl]-; 1704096-35-4; Suzuki coupling reagent CAS 1704096-35-4
EINECS	Contact for details

Quality Control

Our (3-Fluoro-4-(n-Isopropylsulfamoyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.