Description

(3-Fluoro-4-(2-(4-Methylpiperidin-1-Yl)Ethoxy)Phenyl)Boronic Acid Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block. This compound is critical for modern drug discovery, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other biologically active molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex biaryl structures common in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to improve drug potency and selectivity.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals and advanced intermediates.

Basic Information

Product Name	(3-Fluoro-4-(2-(4-Methylpiperidin-1-Yl)Ethoxy)Phenyl)Boronic Acid Hydrochloride
CAS No.	1704095-74-8
Molecular Formula	C14H22BClFNO3
Molecular Weight	317.59 g/mol
Synonyms	[3-Fluoro-4-[2-(4-methyl-1-piperidinyl)ethoxy]phenyl]boronic acid hydrochloride; Boronic acid, B-[3-fluoro-4-[2-(4-methyl-1-piperidinyl)ethoxy]phenyl]-, hydrochloride (1:1); (3-Fluoro-4-(2-(4-methylpiperidin-1-yl)ethoxy)phenyl)boronic acid HCl; 4-(2-(4-Methylpiperidin-1-yl)ethoxy)-3-fluorophenylboronic acid hydrochloride; CAS 1704095-74-8; 1-Piperidineboronic acid derivative hydrochloride
EINECS	Contact for details

Quality Control

Our (3-Fluoro-4-(2-(4-Methylpiperidin-1-Yl)Ethoxy)Phenyl)Boronic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.