Description

(3-(4-(tert-Butoxycarbonyl)Piperazine-1-Carbonyl)-4-Fluorophenyl)Boronic Acid is a sophisticated boronic acid derivative and a key building block in modern pharmaceutical and agrochemical research. This compound matters for its role as a critical intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex biaryl structures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex drug molecules, particularly those containing biaryl motifs via palladium-catalyzed cross-coupling reactions.
• API Synthesis: Used in the research and process development of novel Active Pharmaceutical Ingredients (APIs), especially in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Research: Serves as an intermediate in the development of new herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures.
• Material Science: Potential use in the synthesis of organic electronic materials and advanced polymers where precise molecular architecture is required.
• Chemical Biology & Proteomics: Can be utilized in the development of chemical probes and affinity ligands for studying biological systems and protein function.
• Library Synthesis for Drug Discovery: Enables the rapid construction of diverse compound libraries for high-throughput screening in medicinal chemistry campaigns.

Basic Information

Item	Details
Product Name	(3-(4-(tert-Butoxycarbonyl)Piperazine-1-Carbonyl)-4-Fluorophenyl)Boronic Acid
CAS No.	1704082-92-7
Molecular Formula	C₁₆H₂₂BFN₂O₄
Molecular Weight	336.17 g/mol
Synonyms	4-Fluoro-3-(4-((tert-butoxycarbonyl)piperazine-1-carbonyl))phenylboronic acid; (3-(4-(Boc)Piperazine-1-Carbonyl)-4-Fluorophenyl)Boronic Acid; Boc-Pip-F-Ph-B(OH)₂; tert-Butyl 4-(5-borono-2-fluorobenzoyl)piperazine-1-carboxylate; (3-Carboxy-4-fluorophenyl)boronic acid piperazine-Boc derivative; 1704082-92-7; Boronic acid, B-[3-[[4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl]carbonyl]-4-fluorophenyl]-
EINECS	Contact for details

Quality Control

Our (3-(4-(tert-Butoxycarbonyl)Piperazine-1-Carbonyl)-4-Fluorophenyl)Boronic Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with complete analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (argon/nitrogen) when possible to maintain stability and purity. Keep container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.