Description

(2-Fluoro-4-((4-Methylpiperidin-1-Yl)Methyl)Phenyl)Boronic Acid is a high-purity, synthetically valuable boronic acid derivative featuring a fluorinated phenyl core and a 4-methylpiperidine moiety. This compound is a critical building block in modern organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, due to the presence of the piperidine scaffold.
• Agrochemical Research: Used in creating advanced active ingredients for crop protection products, leveraging the boronic acid group for structural diversification.
• Material Science: Serves as a monomer or linker in the development of organic electronic materials, such as polymers for OLEDs, where the fluorine atom can tune electronic properties.
• Chemical Biology & Proteomics: Employed as a handle for bioconjugation and the development of chemical probes and inhibitors for studying biological pathways.
• Catalyst Ligand Synthesis: The structural elements can be incorporated into sophisticated ligand systems for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	(2-Fluoro-4-((4-Methylpiperidin-1-Yl)Methyl)Phenyl)Boronic Acid
CAS No.	1704064-21-0
Molecular Formula	C13H19BFNO2
Molecular Weight	251.11 g/mol
Synonyms	[2-Fluoro-4-[(4-methyl-1-piperidinyl)methyl]phenyl]boronic acid; B-[2-Fluoro-4-[(4-methyl-1-piperidinyl)methyl]phenyl]boronic acid; 2-Fluoro-4-((4-methylpiperidin-1-yl)methyl)benzeneboronic acid; (2-Fluoro-4-((4-methylpiperidin-1-yl)methyl)phenyl)boronic acid; 4-[(4-Methylpiperidin-1-yl)methyl]-2-fluorophenylboronic acid; 1704064-21-0; Boronic acid, B-[2-fluoro-4-[(4-methyl-1-piperidinyl)methyl]phenyl]-
EINECS	Contact for details

Quality Control

Our (2-Fluoro-4-((4-Methylpiperidin-1-Yl)Methyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.