Description

3-Fluoro-4-(2-Morpholinoethoxy)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling it to act as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex pharmaceutical and agrochemical intermediates. This high-purity intermediate is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific fluorinated, morpholino-substituted aromatic motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorinated aromatic core and morpholinoethoxy side chain contribute to biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis and other advanced catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors for OLEDs and OFETs, where precise molecular architecture is required.
• Chemical Biology & Probe Design: Utilized for creating fluorescent probes, enzyme inhibitors, and other tool compounds for biochemical and diagnostic research applications.
• Scale-Up & Process Chemistry: Supplied in bulk quantities for kilo-lab and pilot plant scale reactions to support route development and commercial manufacturing campaigns.

Basic Information

Product Name	3-Fluoro-4-(2-Morpholinoethoxy)Phenylboronic Acid
CAS No.	1704064-15-2
Molecular Formula	C₁₂H₁₇BFNO₄
Molecular Weight	281.08 g/mol
Synonyms	[3-Fluoro-4-(2-morpholin-4-ylethoxy)phenyl]boronic acid; 4-(2-Morpholinoethoxy)-3-fluorophenylboronic acid; 3-Fluoro-4-(2-morpholinoethoxy)benzeneboronic acid; B-[3-Fluoro-4-(2-morpholinoethoxy)phenyl]boronic acid; 1704064-15-2; (3-Fluoro-4-(2-morpholinoethoxy)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(2-Morpholinoethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for water content, to ensure it meets the stringent requirements of advanced chemical synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades (e.g., >97%, >98%, >99%) to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.