Description

4-(2-(4-Ethylpiperazin-1-Yl)Ethoxy)-3-Fluorophenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a boronic acid group for Suzuki-Miyaura cross-coupling reactions with a piperazine moiety that offers excellent solubility and potential for further functionalization. This compound is primarily sought after by pharmaceutical research and development teams, agrochemical innovators, and advanced material scientists for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorophenyl and piperazine motifs for enhanced bioactivity and environmental stability.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLED emitters or charge-transport layers, where its molecular structure can be incorporated into conjugated polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes, inhibitors, or affinity ligands due to its reactive boronic acid group.
• Library Synthesis for Drug Discovery: Facilitates high-throughput parallel and combinatorial synthesis to generate diverse compound libraries for screening against novel biological targets.
• Ligand Development for Catalysis: The piperazine-ethoxy side chain can be utilized to develop novel ligands for transition metal catalysis.

Basic Information

Product Name	4-(2-(4-Ethylpiperazin-1-Yl)Ethoxy)-3-Fluorophenylboronic Acid
CAS No.	1704064-13-0
Molecular Formula	C14H22BFN2O3
Molecular Weight	296.15 g/mol
Synonyms	3-Fluoro-4-[2-(4-ethyl-1-piperazinyl)ethoxy]benzeneboronic Acid; 4-[2-(4-Ethylpiperazin-1-yl)ethoxy]-3-fluorobenzeneboronic Acid; B-[3-Fluoro-4-[2-(4-ethyl-1-piperazinyl)ethoxy]phenyl]boronic Acid; (3-Fluoro-4-(2-(4-ethylpiperazin-1-yl)ethoxy)phenyl)boronic Acid; 1704064-13-0; 4-(2-(4-Ethyl-1-piperazinyl)ethoxy)-3-fluorophenylboronic Acid; AKOS025310647; FT-0776939
EINECS	Contact for details

Quality Control

Our production of 4-(2-(4-Ethylpiperazin-1-Yl)Ethoxy)-3-Fluorophenylboronic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.