Description

3-Fluoro-4-(2-(4-Oxopiperidin-1-Yl)Ethoxy)Phenylboronic Acid is a sophisticated boronic acid derivative and a key synthetic intermediate in modern organic chemistry. This compound is valued for its role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by enabling the creation of complex aromatic scaffolds.
• Material Science: Serves as a monomer or precursor in the synthesis of advanced organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) agents due to its boronic acid functionality.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.
• Ligand Synthesis: Acts as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Fluoro-4-(2-(4-Oxopiperidin-1-Yl)Ethoxy)Phenylboronic Acid
CAS No.	1704064-10-7
Molecular Formula	C13H17BFNO4
Molecular Weight	281.09 g/mol
Synonyms	1-[2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluorophenoxy]ethyl]piperidin-4-one; 3-Fluoro-4-[2-(4-oxopiperidin-1-yl)ethoxy]benzeneboronic acid; [3-Fluoro-4-[2-(4-oxo-1-piperidinyl)ethoxy]phenyl]boronic acid; 4-(2-(4-Oxopiperidin-1-yl)ethoxy)-3-fluorophenylboronic acid; Boronic acid, B-[3-fluoro-4-[2-(4-oxo-1-piperidinyl)ethoxy]phenyl]-; CAS 1704064-10-7; PINACOL ESTER OF 3-FLUORO-4-(2-(4-OXOPIPERIDIN-1-YL)ETHOXY)PHENYLBORONIC ACID (common protected form)
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-4-(2-(4-Oxopiperidin-1-Yl)Ethoxy)Phenylboronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. All material is characterized by advanced analytical techniques including NMR (1H, 13C, 19F, 11B), HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.