Description

4-Fluoro-3-(Isopropoxymethyl)Phenylboronic Acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing fluorinated biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic frameworks for enhanced activity and stability.
• Material Science Research: Employed in the development of organic electronic materials, such as those for OLEDs and semiconductors, where precise molecular architecture is crucial.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the creation of fluorinated molecular probes and tags for studying biological systems and drug-target interactions.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the life sciences sector.

Basic Information

Product Name	4-Fluoro-3-(Isopropoxymethyl)Phenylboronic Acid
CAS No.	1704063-98-8
Molecular Formula	C10H14BFO3
Molecular Weight	212.03 g/mol
Synonyms	[4-Fluoro-3-(isopropoxymethyl)phenyl]boronic acid; (4-Fluoro-3-((1-methylethoxy)methyl)phenyl)boronic acid; Boronic acid, B-[4-fluoro-3-[(1-methylethoxy)methyl]phenyl]-; 4-Fluoro-3-(isopropoxymethyl)benzeneboronic acid; 3-(Isopropoxymethyl)-4-fluorophenylboronic acid; 1704063-98-8; CAS 1704063-98-8
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Isopropoxymethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.