Description

4-Fluoro-3-(Pyrrolidin-1-Ylmethyl)Phenylboronic Acid is a high-value, advanced pharmaceutical intermediate and building block. This compound is critical for modern drug discovery, particularly in the synthesis of complex molecules for targeted therapies. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex biaryl structures, essential for creating new drug candidates.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of potential active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic components.
• Material Science Precursor: Employed in the development of advanced organic electronic materials, such as those used in OLEDs and sensors.
• Chemical Biology Probes: Facilitates the creation of labeled compounds and probes for studying biological pathways and protein interactions.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries to identify new leads in drug discovery programs.

Basic Information

Product Name	4-Fluoro-3-(Pyrrolidin-1-Ylmethyl)Phenylboronic Acid
CAS No.	1704063-89-7
Molecular Formula	C₁₁H₁₅BFNO₂
Molecular Weight	223.05 g/mol
Synonyms	[4-Fluoro-3-(pyrrolidin-1-ylmethyl)phenyl]boronic acid; (4-Fluoro-3-((pyrrolidin-1-yl)methyl)phenyl)boronic acid; 3-(Pyrrolidin-1-ylmethyl)-4-fluorobenzeneboronic acid; 4-Fluoro-3-(1-pyrrolidinylmethyl)benzeneboronic acid; Boronic acid, B-[4-fluoro-3-[(1-pyrrolidinyl)methyl]phenyl]-; 1704063-89-7; 4-Fluoro-3-(pyrrolidin-1-ylmethyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Pyrrolidin-1-Ylmethyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for sensitive coupling reactions. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.