Description

2-(Ethoxymethyl)-4-Fluorophenylboronic Acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorophenyl moiety enhances biological activity and stability.
• Material Science Research: Building block for the development of organic electronic materials, such as OLEDs and semiconductors, via palladium-catalyzed cross-coupling.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing sophisticated ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the creation of fluorinated molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for bespoke synthesis projects requiring high-fidelity boronic acid derivatives.

Basic Information

Product Name	2-(Ethoxymethyl)-4-Fluorophenylboronic Acid
CAS No.	1704063-87-5
Molecular Formula	C9H12BFO3
Molecular Weight	197.99 g/mol
Synonyms	4-Fluoro-2-(ethoxymethyl)benzeneboronic Acid; [2-(Ethoxymethyl)-4-fluorophenyl]boronic Acid; 2-(Ethoxymethyl)-4-fluorobenzeneboronic Acid; B-[2-(Ethoxymethyl)-4-fluorophenyl]boronic Acid; 1704063-87-5; 4-Fluoro-2-ethoxymethylphenylboronic Acid; (2-(Ethoxymethyl)-4-fluorophenyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 2-(Ethoxymethyl)-4-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.