Description

4-Fluoro-2-((4-Methylpiperazin-1-Yl)Methyl)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group with a substituted piperazine moiety, enabling its use in complex coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients through Suzuki-Miyaura cross-coupling.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Suzuki-Miyaura Cross-Coupling Reagent: Used to form carbon-carbon bonds for constructing complex biaryl structures found in advanced materials and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science: A building block for creating organic electronic materials and advanced polymers with specific functional properties.

Basic Information

Product Name	4-Fluoro-2-((4-Methylpiperazin-1-Yl)Methyl)Phenylboronic Acid
CAS No.	1704063-83-1
Molecular Formula	C12H18BFN2O2
Molecular Weight	252.10 g/mol
Synonyms	[4-Fluoro-2-[(4-methyl-1-piperazinyl)methyl]phenyl]boronic Acid; 2-[(4-Methylpiperazin-1-yl)methyl]-4-fluorophenylboronic Acid; 4-Fluoro-2-((4-methylpiperazin-1-yl)methyl)benzeneboronic Acid; B-[4-Fluoro-2-[(4-methyl-1-piperazinyl)methyl]phenyl]boronic Acid; 1704063-83-1; 4-Fluoro-2-((4-methylpiperazin-1-yl)methyl)phenylboronic acid pinacol ester (common precursor)
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-((4-Methylpiperazin-1-Yl)Methyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.