Description

2-(Dimethylamino)-5-(Trifluoromethyl)Phenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its molecular structure, featuring both a boronic acid group and a trifluoromethyl substituent, makes it a highly valuable intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries. It enables the synthesis of novel active ingredients through efficient cross-coupling reactions.

Application

This advanced boronic acid derivative is utilized in several high-value chemical synthesis pathways, including:

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where the trifluoromethyl group often enhances biological activity and metabolic stability.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful in the synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	2-(Dimethylamino)-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1704063-80-8
Molecular Formula	C9H11BF3NO2
Molecular Weight	217.00 g/mol
Synonyms	[2-(Dimethylamino)-5-(trifluoromethyl)phenyl]boronic acid; 2-(Dimethylamino)-5-(trifluoromethyl)benzeneboronic acid; 2-(N,N-Dimethylamino)-5-(trifluoromethyl)phenylboronic acid; 5-(Trifluoromethyl)-2-(dimethylamino)phenylboronic acid; 2-Dimethylamino-5-trifluoromethylphenylboronic acid; Boronic acid, B-[2-(dimethylamino)-5-(trifluoromethyl)phenyl]-; (2-(Dimethylamino)-5-(trifluoromethyl)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 2-(Dimethylamino)-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.