Description

2-Morpholino-5-(Trifluoromethyl)Phenylboronic Acid is a high-value, multifunctional boronic acid derivative designed for advanced synthetic chemistry. This compound is a critical building block in modern pharmaceutical and agrochemical research, enabling the construction of complex molecules through efficient cross-coupling reactions. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the trifluoromethyl and morpholino groups for enhanced bioactivity and metabolic stability.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, such as OLEDs and OFETs, due to its electron-deficient aromatic system.
• Chemical Biology & Proteomics: Employed in the synthesis of chemical probes and affinity tags for studying protein function and enzyme activity.
• Ligand Development: Acts as a starting material for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring high-purity, specialized boronic acids.

Basic Information

Product Name	2-Morpholino-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1704063-79-5
Molecular Formula	C11H13BF3NO3
Molecular Weight	275.04 g/mol
Synonyms	[2-(Morpholin-4-yl)-5-(trifluoromethyl)phenyl]boronic acid; 2-Morpholino-5-(trifluoromethyl)benzeneboronic acid; 4-[4-(Trifluoromethyl)-2-boronophenyl]morpholine; (2-Morpholino-5-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[2-(4-morpholinyl)-5-(trifluoromethyl)phenyl]-; 1704063-79-5; 2-Morpholin-4-yl-5-trifluoromethylphenylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Morpholino-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.