Description

3-Bromo-4-Chloro-2-Fluoro-Benzoic Acid is a high-purity, multi-halogenated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the halogen atoms contribute to bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for synthesizing advanced polymers, liquid crystals, and organic electronic materials due to its ability to modify molecular polarity and intermolecular interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated aromatic frameworks.

Basic Information

Product Name	3-Bromo-4-Chloro-2-Fluoro-Benzoic Acid
CAS No.	1677706-23-8
Molecular Formula	C7H3BrClFO2
Molecular Weight	253.45 g/mol
Synonyms	2-Fluoro-3-bromo-4-chlorobenzoic acid; Benzoic acid, 3-bromo-4-chloro-2-fluoro-; 3-Bromo-4-chloro-2-fluorobenzoic acid; 4-Chloro-3-bromo-2-fluorobenzoic acid; 2-Fluoro-4-chloro-3-bromobenzoic acid; BCFBA (abbreviation); 1677706-23-8 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-4-Chloro-2-Fluoro-Benzoic Acid adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specification parameters are provided with each shipment. We support cGMP (current Good Manufacturing Practice) standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.