Description

(R)-(-)-2-Pyrrolidinemethanol Hydrochloride CAS NO 1635389-95-5 is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. Its value lies in its enantiomeric purity, which is critical for developing active pharmaceutical ingredients (APIs) with specific stereochemical requirements. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel chiral molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalysis: Used as a precursor or ligand in the synthesis of chiral catalysts for stereoselective chemical transformations.
• Agrochemical Synthesis: Building block for creating chiral active ingredients in herbicides, fungicides, and pesticides where specific stereochemistry affects biological activity.
• Academic & Process Research: Serves as a standard and starting material in methodological development for organic and medicinal chemistry research.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	(R)-(-)-2-Pyrrolidinemethanol Hydrochloride
CAS No.	1635389-95-5
Molecular Formula	C5H12ClNO
Molecular Weight	137.61 g/mol
Synonyms	(R)-2-(Hydroxymethyl)pyrrolidine hydrochloride; (R)-Pyrrolidin-2-ylmethanol hydrochloride; (2R)-2-Pyrrolidinemethanol hydrochloride; (R)-(-)-2-Pyrrolidinemethanol HCl; (R)-2-Pyrrolidinemethanol hydrochloride; (R)-Prolinol hydrochloride; (R)-2-Hydroxymethylpyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-(-)-2-Pyrrolidinemethanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.