Description

3-Bromo-4-Fluoro-5-Iodobenzoic Acid is a highly functionalized benzoic acid derivative that serves as a critical multi-halogenated building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile precursor for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require precise, high-purity intermediates for coupling reactions and further functionalization.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry for creating libraries of bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides that require halogenated aromatic cores.
• Material Science Precursor: Serves as a monomer or starting material for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions due to the presence of bromo and iodo substituents.
• Ligand and Catalyst Development: Utilized in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating chemical libraries.

Basic Information

Product Name	3-Bromo-4-Fluoro-5-Iodobenzoic Acid
CAS No.	1628539-97-8
Molecular Formula	C7H3BrFIO2
Molecular Weight	354.90 g/mol
Synonyms	5-Iodo-3-bromo-4-fluorobenzoic Acid; Benzoic acid, 3-bromo-4-fluoro-5-iodo-; 3-Bromo-4-fluoro-5-iodobenzoic acid; 4-Fluoro-3-bromo-5-iodobenzoic Acid; 1628539-97-8; 3-Br-4-F-5-I-BA
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluoro-5-Iodobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.