Description

2-(2-Fluoro-5-(Methylsulfonyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile intermediate for the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing fluorinated and sulfonylated aromatic motifs.
• Agrochemical Synthesis: Used to create advanced herbicide and fungicide candidates through palladium-catalyzed cross-coupling reactions.
• Material Science Research: Serves as a monomer or building block for constructing organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and labeled compounds for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-(2-Fluoro-5-(Methylsulfonyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1627596-00-2
Molecular Formula	C13H18BFO4S
Molecular Weight	300.16 g/mol
Synonyms	2-Fluoro-5-(methylsulfonyl)phenylboronic acid pinacol ester; (2-Fluoro-5-(methylsulfonyl)phenyl)boronic acid pinacol ester; 2-Fluoro-5-methanesulfonylbenzeneboronic acid pinacol ester; 5-Boronate-2-fluorophenyl methyl sulfone pinacol ester; 2-(2-Fluoro-5-methanesulfonylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; PINACOL 2-FLUORO-5-(METHYLSULFONYL)PHENYLBORONATE
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-5-(Methylsulfonyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.