Description

(S)-3-[1-(4-Methoxybenzenesulfonyl)-(4S,5S)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-2-Yl]-1,1'-Binaphthalene-2,2'-Diyl Hydrogen Phosphate is a sophisticated chiral organocatalyst and ligand, distinguished by its binaphthyl phosphate core integrated with a chiral imidazoline auxiliary. This compound is engineered to provide exceptional stereocontrol in asymmetric synthesis, enabling the production of enantiomerically pure intermediates critical for advanced pharmaceutical development. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for high-value catalytic transformations.

Application

• Asymmetric Catalysis: Serves as a highly effective chiral ligand or organocatalyst for enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Critical for the asymmetric synthesis of chiral drug candidates and active pharmaceutical ingredients (APIs).
• Methodology Development: Used in academic and industrial R&D for developing new catalytic asymmetric protocols.
• Fine Chemical Production: Enables the manufacture of enantiomerically enriched flavors, fragrances, and specialty materials.
• Agrochemical Research: Applied in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Material Science: Potential use in the development of chiral polymers and advanced functional materials.

Basic Information

Product Name	(S)-3-[1-(4-Methoxybenzenesulfonyl)-(4S,5S)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-2-Yl]-1,1'-Binaphthalene-2,2'-Diyl Hydrogen Phosphate
CAS No.	1621994-95-3
Molecular Formula	C49H37N2O7PS
Molecular Weight	828.87 g/mol
Synonyms	(S)-BINOL-Derived Chiral Imidazoline Phosphate; (S)-3-[1-(4-Methoxybenzenesulfonyl)-(4S,5S)-4,5-diphenyl-4,5-dihydro-1H-imidazol-2-yl]-[1,1'-binaphthalene]-2,2'-diyl hydrogenphosphate; (S)-3-[1-(Tosyl)-(4S,5S)-4,5-Diphenyl-4,5-Dihydro-1H-Imidazol-2-Yl]-1,1'-Binaphthalene-2,2'-Diyl Hydrogen Phosphate (analog); Chiral Binaphthyl-Imidazoline Catalyst; (S)-BINAP-Imidazoline Hybrid Ligand; (S)-3-[1-(4-Methoxy-phenylsulfonyl)-(4S,5S)-4,5-diphenyl-imidazolidin-2-yl]-[1,1']binaphthalenyl-2,2'-diyl hydrogen phosphate
EINECS	Contact for details

Quality Control

Our production of this high-value chiral chemical adheres to stringent quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to verify identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting compliance with research and cGMP standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can compromise catalytic activity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.