Description

[S(R)]-n-[(R)-[2-(Diphenylphosphino)Phenyl]-1-Naphthalenylmethyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a key building block in modern asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in transition-metal catalyzed reactions, which is critical for producing single-enantiomer pharmaceutical intermediates and fine chemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity chiral auxiliaries and ligands.

Application

• As a chiral ligand in asymmetric hydrogenation, hydroformylation, and cross-coupling reactions.
• Critical component in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and key intermediates.
• Use in asymmetric catalysis research for developing novel synthetic methodologies.
• Preparation of chiral catalysts for the production of agrochemicals and specialty chemicals.
• Building block for constructing complex molecular architectures in medicinal chemistry.
• Tool for process chemistry optimization in scale-up and manufacturing.

Basic Information

Product Name	[S(R)]-n-[(R)-[2-(Diphenylphosphino)Phenyl]-1-Naphthalenylmethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	1616688-65-3
Molecular Formula	C34H32NOPS
Molecular Weight	533.66 g/mol
Synonyms	(SR)-N-[(R)-[2-(Diphenylphosphino)phenyl]-1-naphthalenylmethyl]-2-methyl-2-propanesulfinamide; (SR,R)-N-[(1-Naphthyl)(2-diphenylphosphinophenyl)methyl]-2-methylpropane-2-sulfinamide; (SR,R)-N-[(1-Naphthyl)(2-diphenylphosphinophenyl)methyl]-tert-butanesulfinamide; Chiral Sulfinamide-Phosphine Ligand; P,N-Ligand; Asymmetric Synthesis Ligand; CAS 1616688-65-3
EINECS	Contact for details

Quality Control

Our production of this advanced chiral ligand adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is fully characterized and tested to meet the exacting standards required for asymmetric catalysis and pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, chiral purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.