Description

[S(R)]-n-[(R)-[2-(Diphenylphosphino)Phenyl]Phenylmethyl]-2-Methyl-2-Propanesulfinamide is a sophisticated chiral sulfinamide-phosphine hybrid ligand, a key building block in asymmetric synthesis. Its value lies in enabling highly enantioselective transformations, crucial for producing single-isomer active pharmaceutical ingredients (APIs) and fine chemicals with superior purity and efficacy. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity chiral auxiliaries and ligands.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation, cross-coupling, and C-H activation.
• As a chiral auxiliary in the stereoselective synthesis of complex organic molecules and natural products.
• For the development of novel catalytic systems in academic and industrial research laboratories.
• In the synthesis of enantiomerically pure intermediates for pharmaceutical active ingredients (APIs).
• For process chemistry optimization in the scale-up of chiral drug candidates.
• In the preparation of specialty chemicals and advanced materials requiring precise stereochemical control.

Basic Information

Item	Details
Product Name	[S(R)]-n-[(R)-[2-(Diphenylphosphino)Phenyl]Phenylmethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	1616688-59-5
Molecular Formula	C29H30NOPS
Molecular Weight	471.59 g/mol
Synonyms	(R)-2-Methyl-2-propanesulfinamide, N-[(1R)-1-[2-(Diphenylphosphino)phenyl]-1-phenylethyl]-; (R)-N-((R)-1-(2-(Diphenylphosphino)phenyl)-1-phenylethyl)-2-methylpropane-2-sulfinamide; Chiral Sulfinamide-Phosphine Ligand; tert-Butanesulfinamide Derivative; Asymmetric Synthesis Ligand; P,N-Ligand; CAS 1616688-59-5
EINECS	Contact for details

Quality Control

Our [S(R)]-n-[(R)-[2-(Diphenylphosphino)Phenyl]Phenylmethyl]-2-Methyl-2-Propanesulfinamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral HPLC, NMR, and elemental analysis, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.