Description

Trimethylsilyl 2,3,4,5-Tetrafluorobenzoate is a high-purity organosilicon reagent featuring a perfluorinated aromatic system. This compound is valued for its role as a versatile synthetic intermediate and protecting group in advanced organic synthesis, particularly for introducing fluorinated benzoate moieties. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise fluorination and silicon-based chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides with enhanced biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic components in electronic display and lighting materials.
• Polymer Modification: Imparts fluorinated aromatic groups into polymer backbones to alter surface properties, thermal stability, and chemical resistance.
• Protecting Group Chemistry: Acts as a trimethylsilyl (TMS) protecting agent for carboxylic acids in multi-step synthetic sequences.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and nucleophilic aromatic substitution reactions due to the activated fluorinated ring.

Basic Information

Product Name	Trimethylsilyl 2,3,4,5-Tetrafluorobenzoate
CAS No.	1616373-58-0
Molecular Formula	C10H11F4O2Si
Molecular Weight	267.27 g/mol
Synonyms	2,3,4,5-Tetrafluorobenzoic Acid Trimethylsilyl Ester; Benzoic Acid, 2,3,4,5-Tetrafluoro-, Trimethylsilyl Ester; Trimethylsilyl Tetrafluorobenzoate; TMS 2,3,4,5-Tetrafluorobenzoate; (2,3,4,5-Tetrafluorobenzoyloxy)trimethylsilane; Trimethyl(2,3,4,5-tetrafluorobenzoyloxy)silane
EINECS	Contact for details

Quality Control

Our Trimethylsilyl 2,3,4,5-Tetrafluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.