Description

(6-(Piperidin-1-Yl)-5-(Trifluoromethyl)Pyridin-3-Yl)Boronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its molecular structure, featuring a piperidine ring and a trifluoromethyl group, makes it a crucial building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-targeted therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, due to its ability to modify electronic properties.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of activity-based probes for target identification and validation.
• Catalyst Ligand Precursor: Can be utilized to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis.
• Library Synthesis for HTS: A valuable reagent for the parallel and combinatorial synthesis of diverse compound libraries for high-throughput screening (HTS) campaigns.

Basic Information

Product Name	(6-(Piperidin-1-Yl)-5-(Trifluoromethyl)Pyridin-3-Yl)Boronic Acid
CAS No.	1610733-89-5
Molecular Formula	C11H14BF3N2O2
Molecular Weight	274.05 g/mol
Synonyms	5-(Trifluoromethyl)-6-(1-piperidinyl)-3-pyridineboronic acid; [6-(Piperidin-1-yl)-5-(trifluoromethyl)pyridin-3-yl]boronic acid; (6-Piperidin-1-yl-5-trifluoromethylpyridin-3-yl)boronic acid; Boronic acid, B-[6-(1-piperidinyl)-5-(trifluoromethyl)-3-pyridinyl]-; 3-Pyridineboronic acid, 5-(trifluoromethyl)-6-(1-piperidinyl)-; CAS 1610733-89-5
EINECS	Contact for details

Quality Control

Our (6-(Piperidin-1-Yl)-5-(Trifluoromethyl)Pyridin-3-Yl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 13C, 11B), HPLC, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.