Description

3-Chloro-5-(Trifluoromethoxy)Cinnamic Acid is a high-purity, multi-functional organic building block characterized by its unique halogenated and trifluoromethoxy-substituted aromatic structure. This compound is essential for advanced chemical synthesis, offering a versatile scaffold for introducing specific steric and electronic properties into target molecules. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for anti-inflammatory and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating specialized organic electronic materials due to its rigid, conjugated structure and fluorine content.
• Polymer Modification: Employed to synthesize functional monomers that impart specific properties like hydrophobicity or chemical resistance to advanced polymers.
• Chemical Research & Development: A valuable reagent for academic and industrial research in medicinal chemistry and material science for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical manufacturers for producing bespoke compounds and complex molecules for client-specific projects.

Basic Information

Product Name	3-Chloro-5-(Trifluoromethoxy)Cinnamic Acid
CAS No.	1588505-18-3
Molecular Formula	C10H6ClF3O3
Molecular Weight	266.60 g/mol
Synonyms	(E)-3-(3-Chloro-5-(trifluoromethoxy)phenyl)acrylic acid; 3-Chloro-5-(trifluoromethoxy)cinnamate; (3-Chloro-5-(trifluoromethoxy)phenyl)acrylic acid; 2-Propenoic acid, 3-(3-chloro-5-(trifluoromethoxy)phenyl)-, (E)-; 1588505-18-3; 3-Chloro-5-trifluoromethoxycinnamic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(Trifluoromethoxy)Cinnamic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.