Description

3-(4-Fluorophenyl)Propylboronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters because it serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules for advanced materials and pharmaceuticals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel fluorinated compounds. The CAS number for this product is 1570510-53-0.

Application

This versatile boronic ester is a key reagent in several high-value synthetic transformations:

• Suzuki-Miyaura Cross-Coupling Reactions: As a stable boronic acid derivative for forming carbon-carbon bonds with aryl/vinyl halides, crucial for constructing biaryl and complex aromatic systems in drug discovery.
• Pharmaceutical Intermediate Synthesis: For the incorporation of the 4-fluorophenylpropyl moiety into active pharmaceutical ingredients (APIs), particularly in CNS and oncology drug candidates.
• Agrochemical Research: Used in the development of novel herbicides and fungicides that leverage the fluorinated aromatic structure for enhanced bioactivity and stability.
• Liquid Crystal & OLED Material Development: Acts as a building block for fluorinated organic semiconductors and advanced display materials.
• Polymer Chemistry: Employed in the synthesis of specialty polymers with tailored properties, such as improved thermal stability or specific optical characteristics.
• Chemical Biology & Probe Development: Useful for creating fluorinated molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	3-(4-Fluorophenyl)Propylboronic Acid Pinacol Ester
CAS No.	1570510-53-0
Molecular Formula	C15H22BFO2
Molecular Weight	264.14 g/mol
Synonyms	3-(4-Fluorophenyl)propane-1-boronic acid pinacol ester; (3-(4-Fluorophenyl)propyl)boronic acid pinacol ester; 4-Fluorophenylpropylboronic acid pinacol ester; Pinacol [3-(4-fluorophenyl)propyl]boronate; (3-(p-Fluorophenyl)propyl)boronic acid pinacol ester; B-[3-(4-Fluorophenyl)propyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1570510-53-0
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)Propylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent hydrolysis and maintain reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.