Description

5-Chloro-4-Fluoro-2-Methoxy-Benzoic Acid is a high-purity, multi-functional benzoic acid derivative distinguished by its specific halogen and methoxy substitution pattern. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile organic synthesis building block for constructing complex molecules. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce its unique structural motif into target compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzoic acid core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where its halogenated structure contributes to biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material or intermediate in the manufacture of specialty electronic chemicals for display technologies.
• Organic Ligand & Catalyst Development: Employed in the preparation of complex ligands for metal-organic frameworks (MOFs) or catalytic systems.
• Custom Synthesis & Contract Manufacturing: A valuable substrate for custom chemical synthesis services and scale-up projects.
• Academic & Industrial R&D: Used in research laboratories for methodological studies and the development of new synthetic pathways.

Basic Information

Product Name	5-Chloro-4-Fluoro-2-Methoxy-Benzoic Acid
CAS No.	1555667-91-8
Molecular Formula	C8H6ClFO3
Molecular Weight	204.58 g/mol
Synonyms	5-Chloro-4-fluoro-2-methoxybenzoic acid; 2-Methoxy-5-chloro-4-fluorobenzoic acid; Benzoic acid, 5-chloro-4-fluoro-2-methoxy-; 4-Fluoro-5-chloro-2-methoxybenzoic acid; 1555667-91-8; 5-Chloro-4-fluoro-2-methoxy-benzoic acid; 2-Methoxy-4-fluoro-5-chlorobenzoic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Fluoro-2-Methoxy-Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent composition. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.