Description

3-Bromo-6-Fluoro-2-Hydroxybenzoic Acid is a high-purity, multi-functional halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromine, fluorine, and hydroxyl substituents, makes it an exceptionally versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores to modulate bioactivity, metabolic stability, and lipophilicity.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the bromo and fluoro substituents can enhance binding affinity and environmental persistence.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle or linker in the design of chemical probes, affinity tags, and bioconjugation reagents for studying biological systems.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to construct complex polycyclic structures.

Basic Information

Product Name	3-Bromo-6-Fluoro-2-Hydroxybenzoic Acid
CAS No.	1538235-22-1
Molecular Formula	C7H4BrFO3
Molecular Weight	235.01 g/mol
Synonyms	2-Hydroxy-3-bromo-6-fluorobenzoic Acid; 3-Bromo-6-fluoro-2-hydroxybenzoic acid; 3-Bromo-6-fluorosalicylic Acid; 6-Fluoro-3-bromo-2-hydroxybenzoic Acid; Benzoic acid, 3-bromo-6-fluoro-2-hydroxy-; 1538235-22-1; 3-Br-6-F-2-OH-BA
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Fluoro-2-Hydroxybenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.