Description

4-Fluoro-5-Iodo-2-Methyl-Benzoic Acid Methyl Ester is a high-purity, multi-functional organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing halogenated aromatic systems for targeted drug discovery.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine and iodine substituents can modulate biological activity and stability.
• Liquid Crystal & OLED Material Synthesis: Acts as a building block for creating advanced organic electronic materials and liquid crystal compounds due to its halogenated aromatic structure.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to create complex biaryl structures.
• Fluorine Chemistry Studies: Utilized in research focused on introducing fluorine atoms into complex molecules to alter their physicochemical and metabolic properties.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in related chemical processes.

Basic Information

Item	Details
Product Name	4-Fluoro-5-Iodo-2-Methyl-Benzoic Acid Methyl Ester
CAS No.	1533441-19-8
Molecular Formula	C9H8FIO2
Molecular Weight	294.06 g/mol
Synonyms	Methyl 4-Fluoro-5-Iodo-2-Methylbenzoate; 2-Methyl-4-fluoro-5-iodobenzoic Acid Methyl Ester; Benzoic acid, 4-fluoro-5-iodo-2-methyl-, methyl ester; 4-Fluoro-5-iodo-o-toluic Acid Methyl Ester; Methyl 4-Fluoro-5-Iodo-o-toluate
EINECS	Contact for details

Quality Control

Our 4-Fluoro-5-Iodo-2-Methyl-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.