Description

Ethyl 2,6-Difluoro-3-Iodobenzoate is a high-purity, multi-functional halogenated aromatic building block. This compound is valued for its precise molecular architecture, which enables efficient synthesis of complex molecules in advanced research and development. It is primarily utilized by pharmaceutical and agrochemical R&D chemists for constructing novel active ingredients, particularly in the development of fluorinated and iodinated drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated and iodinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the difluoro and iodo substituents can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for advanced organic electronic materials, including liquid crystals and charge-transport molecules, due to its halogenated aromatic core.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck) to create complex biaryl and conjugated systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated benzoate derivatives.

Basic Information

Product Name	Ethyl 2,6-Difluoro-3-Iodobenzoate
CAS No.	1520299-34-6
Molecular Formula	C9H7F2IO2
Molecular Weight	312.06 g/mol
Synonyms	Benzoic acid, 2,6-difluoro-3-iodo-, ethyl ester; Ethyl 2,6-difluoro-3-iodobenzoate; 3-Iodo-2,6-difluorobenzoic acid ethyl ester; Ethyl 3-iodo-2,6-difluorobenzoate; 1520299-34-6; Ethyl 2,6-difluoro-3-iodobenzoate (CAS 1520299-34-6)
EINECS	Contact for details

Quality Control

Our Ethyl 2,6-Difluoro-3-Iodobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Handle and store in accordance with all applicable local, national, and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.