Description

Methyl 4-Bromo-2-Fluoro-5-Iodobenzoate is a high-purity, multi-halogenated benzoate ester, serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a versatile intermediate for constructing complex molecules with precise electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for fluorine- and iodine-containing drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where halogen atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating halogenated aromatic cores in electronic materials, contributing to improved performance in display and lighting technologies.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings, enabling the rapid assembly of complex biaryl and conjugated systems.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.
• Material Science: Intermediate for synthesizing specialized polymers and ligands with tailored properties for catalysis and sensing applications.

Basic Information

Product Name	Methyl 4-Bromo-2-Fluoro-5-Iodobenzoate
CAS No.	1509454-55-0
Molecular Formula	C8H5BrFIO2
Molecular Weight	358.93 g/mol
Synonyms	Methyl 4-bromo-2-fluoro-5-iodobenzoate; Benzoic acid, 4-bromo-2-fluoro-5-iodo-, methyl ester; 4-Bromo-2-fluoro-5-iodobenzoic acid methyl ester; Methyl 4-bromo-2-fluoro-5-iodobenzoic acid ester; 1509454-55-0; Methyl 4-Br-2-F-5-I-benzoate
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromo-2-Fluoro-5-Iodobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.