Description

5-Bromo-4-Fluoro-2-Iodo-Benzoic Acid Methyl Ester is a high-purity, multi-halogenated aromatic building block of significant synthetic utility. This compound is valued for its versatility as a key intermediate in advanced organic synthesis, particularly in the construction of complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting various disease pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure.
• Material Science Research: Serves as a building block for creating specialized organic materials, including liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: The iodine and bromine substituents make it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Stille couplings.
• Medicinal Chemistry Library Development: Employed in high-throughput synthesis to create diverse compound libraries for drug discovery screening.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	5-Bromo-4-Fluoro-2-Iodo-Benzoic Acid Methyl Ester
CAS No.	1509204-33-4
Molecular Formula	C8H5BrFIO2
Molecular Weight	358.93 g/mol
Synonyms	Methyl 5-Bromo-4-Fluoro-2-Iodobenzoate; 2-Iodo-5-Bromo-4-Fluorobenzoic Acid Methyl Ester; Benzoic acid, 5-bromo-4-fluoro-2-iodo-, methyl ester; 5-Bromo-4-fluoro-2-iodobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Fluoro-2-Iodo-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.