Description

Ledipasvir (D-Tartrate) CAS NO 1502654-87-6 is a high-purity pharmaceutical intermediate and active ingredient, specifically the D-tartrate salt form of Ledipasvir. This compound is a critical component in the synthesis of antiviral medications, valued for its role in ensuring therapeutic efficacy and process stability. It is essential for research institutions, pharmaceutical development laboratories, and manufacturers engaged in the production of treatments for hepatitis C virus (HCV) infection.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of direct-acting antiviral (DAA) medications for Hepatitis C.
• Pharmaceutical Intermediate for the synthesis and scale-up production of Ledipasvir-based drug products.
• Reference Standard for analytical method development, validation, and quality control testing in regulatory submissions.
• Research & Development of new antiviral therapies and combination drug regimens in academic and institutional settings.
• Process Chemistry for optimizing manufacturing routes and ensuring batch-to-batch consistency.

Basic Information

Product Name	Ledipasvir (D-Tartrate)
CAS No.	1502654-87-6
Molecular Formula	C₅₃H₅₈F₂N₈O₈ • C₄H₆O₆
Molecular Weight	1089.09 g/mol
Synonyms	Ledipasvir D-Tartrate; GS-5885 D-Tartrate; GS 5885 D-Tartrate; Ledipasvir ditosylate (related salt); N-[(2S,5S)-1-{6-[(2S,5S)-1-{3,5-Difluoro-4-[4-(4-fluorophenyl)piperidin-1-yl]phenyl}-5-(6-fluoro-2-{(2S,5S)-2,5-dihydro-1H-pyrrol-1-yl}-1H-benzimidazol-5-yl)-1,5-dihydro-2H-pyrrol-2-yl]-4-fluoro-1H-benzimidazol-2-yl}-5-methyl-1,5-dihydro-2H-pyrrol-2-yl]methoxycarbonyl]-3-methyl-L-valine D-Tartrate Salt
EINECS	Contact for details

Quality Control

Our Ledipasvir (D-Tartrate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity determination, and residual solvent analysis, to ensure compliance with ICH guidelines and customer-specific requirements. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Chiral Purity	≥99.0%
Related Substances (HPLC)	Total impurities ≤1.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.