Description

2,6-Difluoro-3-Formylbenzoic Acid is a high-value, multi-functional aromatic building block featuring both a carboxylic acid and an aldehyde group on a difluorinated benzene ring. This unique structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, particularly in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors, anti-cancer agents, and other biologically active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro and formyl groups contribute to enhanced activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers, liquid crystals, and organic electronic materials due to its aromatic and electron-withdrawing properties.
• Custom Synthesis and Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2,6-Difluoro-3-Formylbenzoic Acid
CAS No.	1500192-09-5
Molecular Formula	C8H4F2O3
Molecular Weight	186.11 g/mol
Synonyms	3-Formyl-2,6-difluorobenzoic Acid; 2,6-Difluorobenzaldehyde-3-carboxylic Acid; 2,6-Difluoro-3-carboxybenzaldehyde; Benzoic acid, 2,6-difluoro-3-formyl-; 1500192-09-5
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Formylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.