Description

(R)-2-Hydroxy-2’-[(S)-Hydroxy(4-Pyridyl)Methyl]-[1,1’-Binaphthalene] is a sophisticated chiral ligand and building block of significant interest in asymmetric synthesis. Its precise stereochemistry and bifunctional structure make it a valuable tool for creating highly selective catalytic systems. This compound is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the development of novel active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Asymmetric Catalysis: Serves as a key chiral ligand for transition metal-catalyzed reactions, including hydrogenation, C-C bond formation, and oxidation processes.
• Pharmaceutical Intermediate: Used in the research and synthesis of enantiomerically pure drug candidates, particularly for complex molecular targets.
• Chiral Auxiliary: Functions as a resolving agent or auxiliary in stereoselective synthesis to control the configuration of new stereocenters.
• Material Science Research: Investigated as a component for constructing chiral polymers, frameworks, or sensors with specific optical properties.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry and process chemistry laboratories.

Basic Information

Product Name	(R)-2-Hydroxy-2’-[(S)-Hydroxy(4-Pyridyl)Methyl]-[1,1’-Binaphthalene]
CAS No.	1498319-67-7
Molecular Formula	C31H23NO2
Molecular Weight	441.52 g/mol
Synonyms	(R)-2-Hydroxy-2'-[(S)-Hydroxy(pyridin-4-yl)methyl]-1,1'-binaphthalene; (R)-2-Hydroxy-2'-[(S)-Hydroxy(4-pyridinyl)methyl]-1,1'-binaphthyl; NOBIN-Pyridine Chiral Ligand Derivative; Axially Chiral BINOL-Pyridine Hybrid Ligand; 1,1'-Binaphthalene-2,2'-diol, 2'-(hydroxy(4-pyridinyl)methyl)-, (1R)-, (2'S)-; Chiral BINAP Analog Ligand
EINECS	Contact for details

Quality Control

Every batch of (R)-2-Hydroxy-2’-[(S)-Hydroxy(4-Pyridyl)Methyl]-[1,1’-Binaphthalene] is produced and analyzed under strict quality management protocols to ensure high chemical purity and enantiomeric excess (ee). Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, chiral HPLC analysis, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.