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(S)-2-Hydroxy-2’-[(R)-Hydroxy(4-Pyridyl)Methyl]-[1,1’-Binaphthalene] CAS NO 1498319-66-6


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CAS No.:1498319-66-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(S)-2-Hydroxy-2’-[(R)-Hydroxy(4-Pyridyl)Methyl]-[1,1’-Binaphthalene] is a sophisticated chiral ligand and building block of significant interest in advanced organic synthesis. Its precise stereochemistry and bifunctional structure make it a highly valuable catalyst component for asymmetric transformations, enabling the production of enantiomerically pure compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-performance, tailor-made chiral auxiliaries.

Application

  • Asymmetric Catalysis: As a chiral ligand for transition metal-catalyzed reactions, including hydrogenation, cross-coupling, and cycloaddition.
  • Pharmaceutical Intermediate Synthesis: A key building block in the research and development of active pharmaceutical ingredients (APIs) requiring specific stereocenters.
  • Chiral Resolution Agent: Used in the separation of enantiomers for analytical or preparative purposes.
  • Material Science Research: A precursor for constructing chiral polymers, frameworks, or sensors with specific optical properties.
  • Agrochemical Development: Employed in the synthesis of enantiomerically pure herbicides, fungicides, or plant growth regulators.
  • Academic & Industrial R&D: A valuable tool for methodological development in organic and organometallic chemistry.

Basic Information

Product Name (S)-2-Hydroxy-2’-[(R)-Hydroxy(4-Pyridyl)Methyl]-[1,1’-Binaphthalene]
CAS No. 1498319-66-6
Molecular Formula C31H23NO2
Molecular Weight 441.52 g/mol
Synonyms (S)-2-Hydroxy-2'-[(R)-Hydroxy(pyridin-4-yl)methyl]-1,1'-binaphthalene; (S)-2-Hydroxy-2'-[(R)-Hydroxy(4-pyridinyl)methyl]-[1,1'-binaphthalene]; (S)-2-Hydroxy-2'-[(R)-Hydroxy(4-pyridyl)methyl]-1,1'-binaphthyl; Chiral NOBIN-Pyridine Derivative; (S,R)-NOBIN-Pyridine Ligand; 1,1'-Binaphthalene-2,2'-diol derivative; Asymmetric BINOL-Pyridine Hybrid Ligand
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Quality Control

Our production of (S)-2-Hydroxy-2’-[(R)-Hydroxy(4-Pyridyl)Methyl]-[1,1’-Binaphthalene] adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques, including HPLC, NMR, and chiral analysis, to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (HPLC) ≥ 99.0% e.e.
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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