Description

Potassium Trifluoro(4-Fluorobenzyl)Borate is a specialized organoboron reagent, specifically a potassium trifluoroborate salt. This compound is valued for its enhanced stability and handling properties compared to traditional boronic acids, making it a crucial building block in modern synthetic chemistry. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for advanced cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex fluorinated aromatic structures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing fluorinated biaryl and heteroaryl motifs in active pharmaceutical ingredient (API) development.
• Agrochemical Research: Used in the synthesis of novel fluorinated pesticides and herbicides, leveraging the stability of the trifluoroborate moiety.
• Material Science: Serves as a precursor for creating fluorinated organic electronic materials and liquid crystals.
• Suzuki-Miyaura Cross-Coupling Reactions: Provides a stable, air- and moisture-tolerant alternative to boronic acids for palladium-catalyzed C-C bond formation.
• Chemical Biology & Probe Development: Enables the site-specific introduction of fluorobenzyl groups into complex molecules for labeling and study.
• Process Chemistry & Scale-up: Its improved stability makes it suitable for optimizing and scaling synthetic routes from lab to pilot plant.

Basic Information

Product Name	Potassium Trifluoro(4-Fluorobenzyl)Borate
CAS No.	1494466-28-2
Molecular Formula	C7H6BF4K
Molecular Weight	207.03 g/mol
Synonyms	Potassium (4-Fluorobenzyl)trifluoroborate; 4-Fluorobenzyltrifluoroboronic Acid Potassium Salt; Potassium 4-Fluorobenzyltrifluoroborate; (4-Fluorobenzyl)trifluoroborate Potassium Salt; Potassium [(4-Fluorophenyl)methyl]trifluoroboranuide; K-4-Fluorobenzyltrifluoroborate; (4-Fluorobenzyl)BF3K
EINECS	Contact for details

Quality Control

Our Potassium Trifluoro(4-Fluorobenzyl)Borate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 19F, 11B), HPLC, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support compliance with REACH, TSCA, and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.