Description

3-(2-Fluorophenyl)Oxetane-3-Carboxylic Acid is a high-value, fluorinated oxetane building block essential for advanced organic synthesis. This compound is particularly significant for introducing the rigid, polar oxetane moiety into molecular scaffolds, which can modulate physicochemical properties like solubility and metabolic stability. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the oxetane ring can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced polymers and functional materials, where fluorinated oxetanes can impart unique thermal and chemical resistance.
• Chemical Biology Probes: Useful for constructing molecular probes and tags due to its reactive carboxylic acid group and fluorinated aromatic ring.

Basic Information

Product Name	3-(2-Fluorophenyl)Oxetane-3-Carboxylic Acid
CAS No.	1486834-14-3
Molecular Formula	C10H9FO3
Molecular Weight	196.18 g/mol
Synonyms	3-(2-Fluorophenyl)oxetane-3-carboxylic acid; 2-Fluoro-α,α-dimethylbenzenepropanoic acid, oxetane analog; 3-Carboxy-3-(2-fluorophenyl)oxetane; Oxetane-3-carboxylic acid, 3-(2-fluorophenyl)-; 1486834-14-3; 3-(2-Fluorophenyl)-3-oxetanecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Fluorophenyl)Oxetane-3-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by techniques such as HPLC, NMR, and IR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.