Description

2-Amino-4-Chloro-5-Trifluoromethyl-Benzoic Acid CAS NO 1476759-55-3 is a high-value, multi-functional benzoic acid derivative characterized by its trifluoromethyl and amino-chloro substitution pattern. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for the synthesis of complex organic molecules. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and anticancer therapies.
• Agrochemical Synthesis: Used as a building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the biological activity imparted by the trifluoromethyl group.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers due to its unique electronic properties.
• Custom Synthesis and Contract Manufacturing: A vital substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Amino-4-Chloro-5-Trifluoromethyl-Benzoic Acid
CAS No.	1476759-55-3
Molecular Formula	C8H5ClF3NO2
Molecular Weight	239.58 g/mol
Synonyms	5-Trifluoromethyl-2-amino-4-chlorobenzoic acid; 4-Chloro-2-amino-5-(trifluoromethyl)benzoic acid; 2-Amino-4-chloro-α,α,α-trifluoro-m-toluic acid; Benzoic acid, 2-amino-4-chloro-5-(trifluoromethyl)-; 2-Amino-4-chloro-5-trifluoromethylbenzoic acid; ACFBA; 1476759-55-3
EINECS	Contact for details

Quality Control

Our production of 2-Amino-4-Chloro-5-Trifluoromethyl-Benzoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.