Description

3-(Cyanomethyl)-5-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its dual functional groups, enabling precise cross-coupling reactions essential for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

This versatile boronic acid ester serves as a key intermediate in several high-value chemical synthesis pathways:

• Pharmaceutical Intermediates: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require fluorinated aromatic components.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and semiconductors.
• Chemical Biology & Probe Development: Serves as a building block for creating fluorescent tags, enzyme inhibitors, and other molecular probes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and libraries for drug discovery programs.

Basic Information

Product Name	3-(Cyanomethyl)-5-Fluorobenzeneboronic Acid
CAS No.	1460307-63-4
Molecular Formula	C8H7BFNO2
Molecular Weight	178.96 g/mol
Synonyms	5-Fluoro-3-(cyanomethyl)benzeneboronic Acid; (5-Fluoro-3-(cyanomethyl)phenyl)boronic Acid; 3-Cyanomethyl-5-fluorophenylboronic Acid; 5-Fluoro-3-cyanomethylphenylboronic Acid; 1460307-63-4; Boronic acid, B-[5-fluoro-3-(cyanomethyl)phenyl]-; AKOS040759186
EINECS	Contact for details

Quality Control

Our 3-(Cyanomethyl)-5-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.