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3-Chloro-5-Fluoro-4-(Methoxymethoxy)Phenylboronic Acid CAS NO 1451392-28-1


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CAS No.:1451392-28-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Chloro-5-Fluoro-4-(Methoxymethoxy)Phenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and advanced organic materials.

Application

  • Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
  • Agrochemical Research: Used in the development of advanced herbicides and fungicides, leveraging its halogenated aromatic structure for bioactivity.
  • Material Science: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, such as polymers for OLEDs.
  • Chemical Synthesis: Employed as a versatile reagent for introducing the substituted phenylboronic acid moiety into complex molecules in academic and industrial R&D.
  • Ligand Synthesis: Useful for creating specialized ligands for catalysis and sensor development due to its boronic acid functional group.

Basic Information

Item Details
Product Name 3-Chloro-5-Fluoro-4-(Methoxymethoxy)Phenylboronic Acid
CAS No. 1451392-28-1
Molecular Formula C8H9BClFO4
Molecular Weight 233.42 g/mol
Synonyms [3-Chloro-5-fluoro-4-(methoxymethoxy)phenyl]boronic acid; (3-Chloro-5-fluoro-4-methoxymethoxyphenyl)boronic acid; 3-Chloro-5-fluoro-4-(MOM)phenylboronic acid; Boronic acid, B-[3-chloro-5-fluoro-4-(methoxymethoxy)phenyl]-; 1451392-28-1; 3-Chloro-5-fluoro-4-methoxymethoxybenzeneboronic acid
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Quality Control

Our 3-Chloro-5-Fluoro-4-(Methoxymethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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