Description

3-Fluoro-2-Formyl-6-Methoxyphenylboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both formyl and boronic acid functional groups on a fluorinated aromatic ring, makes it a versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients through cross-coupling reactions and other advanced synthetic methodologies.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or linker for creating functionalized polymers, organic frameworks, and advanced materials with specific electronic or optical properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and sensors that utilize boronic acid-diol interactions for detecting sugars or other biomolecules.
• Ligand Development: Acts as a starting material for synthesizing specialized ligands used in catalysis and metal-organic chemistry.
• Custom Synthesis & Contract Manufacturing: A high-value intermediate for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	3-Fluoro-2-Formyl-6-Methoxyphenylboronic Acid
CAS No.	1451392-14-5
Molecular Formula	C8H8BFO4
Molecular Weight	197.96 g/mol
Synonyms	(3-Fluoro-2-formyl-6-methoxyphenyl)boronic acid; 2-Borono-3-fluoro-6-methoxybenzaldehyde; 3-Fluoro-6-methoxy-2-formylbenzeneboronic acid; 3-Fluoro-2-formyl-6-methoxybenzeneboronic acid; 1451392-14-5; 3-Fluoro-6-methoxy-2-carboxaldehydephenylboronic acid; 2-Formyl-3-fluoro-6-methoxyphenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Formyl-6-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.