Description

2-Fluoro-6-Methoxy-3-Methylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules via cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable synthetic intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing complex biaryl or heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific fluorinated and methoxylated aromatic motifs.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, including OLEDs and semiconductors.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds under mild conditions.
• Ligand and Catalyst Development: Used to synthesize novel bidentate or tridentate ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the creation of fluorinated molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	2-Fluoro-6-Methoxy-3-Methylphenylboronic Acid
CAS No.	1451392-12-3
Molecular Formula	C8H10BFO3
Molecular Weight	183.98 g/mol
Synonyms	(2-Fluoro-6-methoxy-3-methylphenyl)boronic acid; 2-Fluoro-6-methoxy-3-methylbenzeneboronic acid; 3-Methyl-2-fluoro-6-methoxybenzeneboronic acid; Boronic acid, B-(2-fluoro-6-methoxy-3-methylphenyl)-; 1451392-12-3; 2-Fluoro-6-methoxy-m-tolylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Methoxy-3-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.