Description

2-Fluoro-4-Formyl-6-Methoxyphenylboronic Acid is a specialized organoboron building block featuring both aldehyde and boronic acid functional groups on a fluorinated aromatic scaffold. This unique bifunctional structure makes it a critical intermediate for constructing complex molecules via sequential cross-coupling and condensation reactions. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl compounds and complex drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific fluorinated aromatic structures.
• Material Science Research: Serves as a monomer or building block for creating novel polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Probe Development: Employed in the synthesis of fluorescent tags, molecular probes, and bioconjugates due to its reactive aldehyde and boronic acid groups.
• Catalyst Ligand Synthesis: Useful for constructing sophisticated ligand frameworks for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale API development.

Basic Information

Product Name	2-Fluoro-4-Formyl-6-Methoxyphenylboronic Acid
CAS No.	1451392-10-1
Molecular Formula	C8H8BFO4
Molecular Weight	197.96 g/mol
Synonyms	(2-Fluoro-4-formyl-6-methoxyphenyl)boronic acid; 2-Fluoro-6-methoxy-4-formylbenzeneboronic acid; 4-Borono-3-fluoro-5-methoxybenzaldehyde; 3-Fluoro-5-methoxy-4-boronobenzaldehyde; 2-Fluoro-4-carbaldehyde-6-methoxyphenylboronic acid; 2-Fluoro-4-formyl-6-methoxybenzeneboronic acid; 2-Fluoro-6-methoxy-4-boronobenzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Formyl-6-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.