Description

2-Fluoro-6-Methoxy-4-Methylphenylboronic Acid is a specialized organoboron compound, a key building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in drug discovery for fluorinated compounds.
• Agrochemical Synthesis: Used to create advanced, high-performance herbicides, fungicides, and insecticides with tailored properties.
• Ligand and Catalyst Development: Serves as a building block for creating sophisticated ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where the specific substitution pattern influences electronic properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse R&D projects.

Basic Information

Product Name	2-Fluoro-6-Methoxy-4-Methylphenylboronic Acid
CAS No.	1451392-08-7
Molecular Formula	C8H10BFO3
Molecular Weight	183.98 g/mol
Synonyms	(2-Fluoro-6-methoxy-4-methylphenyl)boronic acid; 2-Fluoro-6-methoxy-4-methylbenzeneboronic acid; 4-Methyl-2-fluoro-6-methoxybenzeneboronic acid; B-(2-Fluoro-6-methoxy-4-methylphenyl)boronic acid; 2-Fluoro-6-methoxy-p-tolylboronic acid; 1451392-08-7 (CAS); Boronic acid, B-(2-fluoro-6-methoxy-4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Methoxy-4-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.